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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPARG All Species: 22.73
Human Site: S456 Identified Species: 62.5
UniProt: P37231 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P37231 NP_005028.4 505 57620 S456 L K L N H P E S S Q L F A K L
Chimpanzee Pan troglodytes XP_001153669 505 57634 S456 L K L N H P E S S Q L F A K L
Rhesus Macaque Macaca mulatta O18924 505 57572 S456 L K L N H P E S S Q L F A K L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P37238 505 57580 S456 L K L N H P E S S Q L F A K V
Rat Rattus norvegicus O88275 505 57549 S456 L K L N H P E S S Q L F A K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P22448 455 50690 P407 M E I P G S M P P L I Q E M L
Frog Xenopus laevis P37234 477 54037 S428 L K L N H P D S A Q L F A K L
Zebra Danio Brachydanio rerio Q90271 444 49906 L396 I P G S M P P L I Q E M L E N
Tiger Blowfish Takifugu rubipres Q9W5Z3 447 49514 P399 M E I P G S M P P L I Q E M L
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.2 N.A. N.A. 96 95.8 N.A. N.A. 21.1 70.6 23.3 21.7 N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 99.8 N.A. N.A. 98 97.8 N.A. N.A. 38 79.8 38 37.6 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 N.A. N.A. 93.3 93.3 N.A. N.A. 6.6 86.6 13.3 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. N.A. 33.3 100 33.3 33.3 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 12 0 0 0 67 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % D
% Glu: 0 23 0 0 0 0 56 0 0 0 12 0 23 12 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 67 0 0 0 % F
% Gly: 0 0 12 0 23 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 67 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 12 0 23 0 0 0 0 0 12 0 23 0 0 0 0 % I
% Lys: 0 67 0 0 0 0 0 0 0 0 0 0 0 67 0 % K
% Leu: 67 0 67 0 0 0 0 12 0 23 67 0 12 0 67 % L
% Met: 23 0 0 0 12 0 23 0 0 0 0 12 0 23 0 % M
% Asn: 0 0 0 67 0 0 0 0 0 0 0 0 0 0 12 % N
% Pro: 0 12 0 23 0 78 12 23 23 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 78 0 23 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 12 0 23 0 67 56 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _